Glutathione Levels and Susceptibility to Chemically Induced Injury in Two Human Prostate Cancer Cell Lines
More aggressive prostate Doors cancer cells (PCCs) are often resistant to chemotherapy.Differences exist in redox status and mitochondrial metabolism that may help explain this phenomenon.Two human PCC lines, PC-3 cells (more aggressive) and LNCaP cells (less aggressive), were compared with regard to cellular glutathione (GSH) levels, susceptibilit